Skip to main content

Funding Opportunity

HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional)

More than 25 million Americans suffer from daily chronic pain, a highly debilitating medical condition that is complex and difficult to manage. In recent decades, there has been an overreliance in the prescription of opioids for chronic pain despite their poor ability to improve function and high addiction liability. This contributed to a significant and alarming epidemic of opioid overdose deaths and addictions. Innovative scientific solutions to develop alternative pain treatment options are thus critically needed. Through targeted research efforts, the NIH HEAL Initiative aims to support the development of safe and effective devices to treat pain with little or no addiction liability. This funding opportunity announcement (FOA) is designed to support interdisciplinary research teams of multiple PD/PIs to investigate the mechanism of action of pain relief by medical devices with the overall goal of optimizing therapeutic outcomes for FDA-approved or -cleared technologies. Program teams are expected to accomplish goals that require considerable synergy and collaborative interactions. Teams must leverage appropriate multi-disciplinary expertise to develop new principles and methods for experimentation, analysis, and interpretation. Teams are encouraged to consider objectives that will produce major advances in the field of pain relief by medical devices.

Post Date:April 27, 2023

Close Date:June 9, 2025

Last Updated Date:April 27, 2023

Opportunity ID: 347797

Opportunity Number: RFA-NS-23-028

Agency Name: National Institutes of Health

Eligible Applicants:

0 - State governments
1 - County governments
2 - City or township governments
4 - Special district goverments
5 - Independent school districts
6 - Public and State controlled institutions of higher education
7 - Native American tribal governments (Federally recognized)
8 - Public housing authorities/Indian housing authorities
11 - Native American tribal organizations (other than Federally recognized tribal governments)
12 - Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education
13 - Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education
20 - Private institutions of higher education
22 - For-profit organizations other than small businesses
23 - Small businesses
25 - Others



Bell icon
Phone icon


Mail icon
BJA logo
IIR logo

© 2024. PDMP TTAC. All Rights Reserved. | Accessibility Information | Notice of Federal Funding & Federal Disclaimer